Pub. Date : 2016 Jan 7
PMID : 25798840
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we show that the expression of beta2-AR, which mediates most catecholamine-induced effects, negatively correlates with trastuzumab response in the patients with Her2-overexpressing breast cancer. | Catecholamines | adrenoceptor beta 2 | Homo sapiens |
| 2 | Thus, trastuzumab resistance-dependent PI3K/Akt/mTOR pathway is controlled by catecholamine-induced beta2-AR activation. | Catecholamines | adrenoceptor beta 2 | Homo sapiens |