Title : β2-AR signaling controls trastuzumab resistance-dependent pathway.

Pub. Date : 2016 Jan 7

PMID : 25798840






1 Functional Relationships(s)
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1 Catecholamine stimulation upregulates the expression of miR-21 and MUC-1 by activating Her2 and STAT3, leading to deficiency of phosphatase and tensin homolog and activation of phosphatidylinositol-3-kinase (PI3K) and Akt. Catecholamines microRNA 21 Homo sapiens