Title : Selective targeting of FAK-Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells.

Pub. Date : 2015 Jun 28

PMID : 25796439






2 Functional Relationships(s)
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1 Selective targeting of FAK-Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells. Doxorubicin protein tyrosine kinase 2 beta Homo sapiens
2 MCF-7/Dox cells expressed constitutively active forms of the tyrosine kinases: focal adhesion kinase (FAK-Y397) and protein tyrosine kinase 2 beta (Pyk2- Y579/580) compared with parental MCF-7 cells. Doxorubicin protein tyrosine kinase 2 beta Homo sapiens