Title : Curcumin enhances the radiosensitivity of U87 cells by inducing DUSP-2 up-regulation.

Pub. Date : 2015

PMID : 25792385






2 Functional Relationships(s)
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1 Furthermore, we observed that curcumin increased DUSP-2 protein expression and decreased the phosphorylation of ERK and JNK. Curcumin mitogen-activated protein kinase 8 Homo sapiens
2 CONCLUSION: Our results suggest that low-dose curcumin may enhance the radiosensitivity of human glioma U87 cells in vitro by inducing G2/M cell cycle arrest through up-regulation of DUSP-2 expression and inhibition of ERK and JNK phosphorylation. Curcumin mitogen-activated protein kinase 8 Homo sapiens