Title : Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K.

Pub. Date : 2016 May

PMID : 25787879






1 Functional Relationships(s)
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1 DGC treatment attenuated TPA-induced activator protein-1 (AP-1) and nuclear factor-kappaB (NF-kappaB) transcriptional activation, two major regulators of TPA-induced cell transformation, and COX-2 expression. Tetradecanoylphorbol Acetate mitochondrially encoded cytochrome c oxidase II Homo sapiens