Title : Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.

Pub. Date : 2015 Mar 17

PMID : 25786174






1 Functional Relationships(s)
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1 In M1 macrophages, we identified a metabolic break at Idh, the enzyme that converts isocitrate to alpha-ketoglutarate, providing mechanistic explanation for TCA cycle fragmentation. isocitric acid isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus