Pub. Date : 2015 Aug
PMID : 25783839
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | LPA was able to diminish LPS-induced phosphorylation of p38 and Akt, as well as NF-kappaB p65 nuclear translocation. | lysophosphatidic acid | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Our findings demonstrate a clear anti-inflammatory role of LPA acting via Galpha(i) in LPS-mediated inflammatory response in macrophages, owing, at least in part, to its suppressive effect on LPS-induced activation of p38, Akt and NF-kappaB. | lysophosphatidic acid | AKT serine/threonine kinase 1 | Homo sapiens |