Pub. Date : 2015
PMID : 25775474
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We aimed at evaluating whether dietary fat with highly enriched (87%) PA in sn-2 position (Hsn-2 PA), by increasing PA incorporation into tissue phospholipids (PL), modifies fatty acid profile and biosynthesis of fatty acid-derived bioactive lipids, such as endocannabinoids and their congeners. | Palmitic Acid | WNK lysine deficient protein kinase 1 | Rattus norvegicus |
| 2 | We aimed at evaluating whether dietary fat with highly enriched (87%) PA in sn-2 position (Hsn-2 PA), by increasing PA incorporation into tissue phospholipids (PL), modifies fatty acid profile and biosynthesis of fatty acid-derived bioactive lipids, such as endocannabinoids and their congeners. | Palmitic Acid | WNK lysine deficient protein kinase 1 | Rattus norvegicus |
| 3 | RESULTS: Rats on Hsn-2 PA diet had lower levels of anandamide with concomitant increase of its congener palmitoylethanolamide and its precursor PA into visceral adipose tissue phospholipids. | Palmitic Acid | WNK lysine deficient protein kinase 1 | Rattus norvegicus |
| 4 | CONCLUSIONS: Dietary Hsn-2 PA, by modifying endocannabinoids and congeners biosynthesis in different tissues may potentially concur in the physiological regulation of energy metabolism, brain function and body fat distribution. | Palmitic Acid | WNK lysine deficient protein kinase 1 | Rattus norvegicus |