Pub. Date : 2015 Jun
PMID : 25772062
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The exposure of the cells to 0.5 mM enalapril and enalaprilat contributed to increase in IGF-IR and alpha2beta1 integrin receptor as well as TGF-beta1 and NF-kappaB p65 expressions. | Enalaprilat | transforming growth factor beta 1 | Homo sapiens |
| 2 | Enalapril- and enalaprilat-dependent increase of collagen biosynthesis in fibroblasts results from increase of prolidase activity and expression, which may undergo through activation of alpha2beta1 integrin and IGF-IR signaling as well as upregulation of TGF-beta1 and NF-kappaB p65, the inhibitor of collagen gene expression. | Enalaprilat | transforming growth factor beta 1 | Homo sapiens |