Title : The mechanism and significance of synergistic induction of the expression of plasminogen activator inhibitor-1 by glucocorticoid and transforming growth factor beta in human ovarian cancer cells.

Pub. Date : 2015 May 15

PMID : 25770462






1 Functional Relationships(s)
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1 TGF-beta-activated p38MAPK and ERK pathways cross-talked with GR pathway to augment the expression of PAI-1 through enhancing DEX-induced GR phosphorylation at Ser211 in ovarian cancer cells. Dexamethasone mitogen-activated protein kinase 1 Homo sapiens