Title : Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

Pub. Date : 2015 Mar 11

PMID : 25766404






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Knockdown (KD) of MDH2 in HeLa cells by shRNA triggered the accumulation of both malate (mean +- SD: wild-type [WT] = 1+-0.18; KD = 2.24+-0.17, P = .043) and fumarate (WT = 1+-0.06; KD = 2.6+-0.25, P = .033), which was reversed by transient introduction of WT MDH2 cDNA. malic acid malate dehydrogenase 2 Homo sapiens