Title : Interleukin 6 inhibits HBV entry through NTCP down regulation.

Pub. Date : 2015 Jul

PMID : 25765005






2 Functional Relationships(s)
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1 In parallel, we observed a 98% decrease in NTCP mRNA steady state level and an 80% reduction in NTCP-mediated taurocholate uptake. Taurocholic Acid solute carrier family 10 member 1 Homo sapiens
2 IL-6-mediated inhibition of NTCP-mediated taurocholate uptake and viral entry exhibited similar dose-dependence and kinetics while restoration of NTCP expression suppressed the inhibitory effect of IL-6. Taurocholic Acid solute carrier family 10 member 1 Homo sapiens