Title : FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction.

Pub. Date : 2015 Jun

PMID : 25762025






1 Functional Relationships(s)
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1 In lung myofibroblasts, which mainly expressed the S1P2 receptor subtype, we showed that FTY720-P selectively activated the Galpha12/13/Rho/ROCK pathway via the S1P2 receptor. FTY 720P G protein subunit alpha 12 Homo sapiens