Title : PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation.

Pub. Date : 2015 Mar 12

PMID : 25761777






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PERK silencing results in decreased glioma cell viability and ATP/lactate production upon low glucose stress, which is mediated by partially blocked AKT activation and subsequent inhibition of Hexokinase II (HK2)"s mitochondria translocation. Lactic Acid hexokinase 2 Homo sapiens