Title : The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation.

Pub. Date : 2015 Jun 1

PMID : 25753732






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Using Cdx1 as an entry point, we identified the retinoid acid (RA) and canonical Wnt pathways as downstream targets of Gpr161. Radium G protein-coupled receptor 161 Mus musculus
2 Intraperitoneal RA injection restores expression of canonical Wnt markers and rescues Gpr161(vl/vl) NTDs. Radium G protein-coupled receptor 161 Mus musculus