Pub. Date : 2015 Apr 17
PMID : 25753205
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Although IDH2 catalyzes the oxidative carboxylation of isocitrate to alpha-ketoglutarate (alpha-KG) in mitochondria, mutated IDH2 proteins possess the ability to change alpha-KG into the oncometabolite R(-)-2-hydroxyglutarate (2-HG). | isocitric acid | isocitrate dehydrogenase (NADP(+)) 2 | Homo sapiens |
| 2 | Although IDH2 catalyzes the oxidative carboxylation of isocitrate to alpha-ketoglutarate (alpha-KG) in mitochondria, mutated IDH2 proteins possess the ability to change alpha-KG into the oncometabolite R(-)-2-hydroxyglutarate (2-HG). | isocitric acid | isocitrate dehydrogenase (NADP(+)) 2 | Homo sapiens |