Title : ERK1/2 acts as a switch between necrotic and apoptotic cell death in ether phospholipid edelfosine-treated glioblastoma cells.

Pub. Date : 2015 May-Jun

PMID : 25749008






1 Functional Relationships(s)
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1 Combined treatment of U0126 and edelfosine totally inhibited ERK1/2 phosphorylation, and led to RIPK1 and RelA/NF-kappaB degradation, together with a strong activation of caspase-3 and -8. U 0126 receptor interacting serine/threonine kinase 1 Homo sapiens