Pub. Date : 2015 May
PMID : 25746764
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL4 receptor alpha mediates enhanced glucose and glutamine metabolism to support breast cancer growth. | Glucose | interleukin 4 | Mus musculus |
2 | In vitro, IL4-enhanced glucose consumption and lactate production in 4T1 cells was mediated by IL4Ralpha. | Glucose | interleukin 4 | Mus musculus |
3 | Our results demonstrate that IL4R mediates enhanced glucose and glutamine metabolism in 4T1 cancer cells, and that IL4-induced growth is supported by IL4/IL4R-enhanced glutamine metabolism in both human and murine mammary cancer cells. | Glucose | interleukin 4 | Mus musculus |