Title : Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.

Pub. Date : 2016 Mar

PMID : 25743373






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibited AChE can be reactivated by cleavage of the Ser-phosphorus bond either spontaneously or through a reaction with nucleophilic agents, such as oximes. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Here, our goal was to study oxime reactivation and aging reactions of human AChE inhibited by mipafox or a sarin analog (Flu-MPs, fluorescent methylphosphonate). Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens