Pub. Date : 2015 Apr
PMID : 25742746
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | All-trans retinoic acid downregulates ALDH1-mediated stemness and inhibits tumour formation in ovarian cancer cells. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |
| 2 | Here, we investigated the ALDH1-regulated function and its underlying signalling and tested whether all-trans retinoic acid (ATRA) can suppress ALDH1-regulated tumour behaviour in ovarian cancer cells. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |
| 3 | Here, we investigated the ALDH1-regulated function and its underlying signalling and tested whether all-trans retinoic acid (ATRA) can suppress ALDH1-regulated tumour behaviour in ovarian cancer cells. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |
| 4 | We conclude that ATRA downregulates ALDH1/FoxM1/Notch1 signalling and suppresses tumour formation in ovarian cancer cells. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |