Title : Co-culture with bone marrow stromal cells protects PC12 neuronal cells from tumor necrosis factor-α-induced apoptosis by inhibiting the tumor necrosis factor receptor/caspase signaling pathway.

Pub. Date : 2015 Jul

PMID : 25738414






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1 Furthermore, Annexin V/propidium iodide staining and flow cytometric analysis demonstrated that TNF-alpha increased PC12-cell apoptosis from 3.49 to 40.74% in the negative control and PC group, and the apoptotic rate was significantly reduced upon co-culture with BMSCs to 16.97%. Propidium tumor necrosis factor Rattus norvegicus