Title : Synthetic isoprenoid photoaffinity labeling of P-glycoprotein specific to multidrug-resistant cells.

Pub. Date : 1989 Nov

PMID : 2573823






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SDB inhibits the photolabeling of P-glycoprotein with the vinblastine analog N-(pazido-(3-(125)l)salicyl)-N"-beta-aminoethylvindesine. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens
2 P-glycoprotein labeling was inhibited by anticancer agents, vinblastine, vincristine, actinomycin D, and daunomycin, with half-maximal inhibition at 2.0, 2.3, 18, and 23 microM, respectively. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens