Pub. Date : 2016 Aug
PMID : 25737032
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, both pazopanib and ketoconazole were docked into the activity cavity of CYP3A4 to compare their binding potential. | Ketoconazole | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | The distance between ketoconazole and activity center (2.10 A) is closer than the distance between pazopanib and activity center of CYP3A4, indicating the easy influence of CYP3A4 inhibitor toward the metabolism of pazopanib. | Ketoconazole | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |