Title : PTEN Inhibits High Glucose-Induced Phenotypic Transition in Podocytes.

Pub. Date : 2015 Aug

PMID : 25736988






2 Functional Relationships(s)
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1 In the present study, we demonstrated that PI3K/Akt pathway was activated in podocytes exposed to high glucose conditions, accompanied by down-regulation of the podocalyxin (PCX) and nephrin expression and up-regulation of the desmin and alpha-smooth muscle actin (alpha-SMA) expression. Glucose podocalyxin like Homo sapiens
2 In the present study, we demonstrated that PI3K/Akt pathway was activated in podocytes exposed to high glucose conditions, accompanied by down-regulation of the podocalyxin (PCX) and nephrin expression and up-regulation of the desmin and alpha-smooth muscle actin (alpha-SMA) expression. Glucose podocalyxin like Homo sapiens