Title : Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1.

Pub. Date : 2015 May

PMID : 25736222






1 Functional Relationships(s)
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1 Our study shows that LXR ligands such as oxysterols, GW3965 or TO901317, as well as RXR ligands like 9cis retinoic acid or SR11237, decreased LPS-induced expression of COX-2 and mPGES-1. Alitretinoin prostaglandin-endoperoxide synthase 2 Homo sapiens