Title : Investigations into the decomposition of aminoacyl-substituted monosaccharide scaffolds from a drug discovery library.

Pub. Date : 2015 Apr 7

PMID : 25736157






1 Functional Relationships(s)
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1 The reaction occurs most likely through an initial intramolecular amino-amide interaction, followed by an N- to O-acyl transfer of the side chain from C-4 to the C-6 position to form an ester intermediate (5), detectable by NMR, and subsequent hydrolysis. Esters complement C6 Homo sapiens