Title : Transglutaminase-mediated cross-linking of fibrinogen by human umbilical vein endothelial cells.

Pub. Date : 1989 Dec 5

PMID : 2573600






2 Functional Relationships(s)
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1 Calcium-dependent binding was completely inhibited by unlabeled fibrinogen, partially inhibited by a monoclonal antibody (7E3) against glycoprotein IIb-IIIa, but not inhibited by fibrinogen fragments D or E, an anti-glycoprotein IIIa polyclonal antibody, or the Arg-Gly-Asp-Ser tetrapeptide. Serine fibrinogen beta chain Homo sapiens
2 In contrast, the Arg-Gly-Asp-Ser tetrapeptide as well as the monoclonal antibody 7E3 markedly inhibited attachment of endothelial cells to substrate-immobilized fibrinogen, whereas fragment D or E did not. Serine fibrinogen beta chain Homo sapiens