Title : Characterizing and optimizing human anticancer drug targets based on topological properties in the context of biological pathways.

Pub. Date : 2015 Apr

PMID : 25724580






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, the performance for mercaptopurine was significant: 6 known targets (ADSL, GMPR2, GMPR, HPRT1, AMPD3, AMPD2) were ranked in the top 15 and other four out of the top 15 (MAT2A, CDKN1A, AREG, JUN) have the potentialities to become new targets for cancer therapy. Mercaptopurine methionine adenosyltransferase 2A Homo sapiens