Title : Structure-based design, structure-activity relationship analysis, and antitumor activity of diaryl ether derivatives.

Pub. Date : 2015 Oct

PMID : 25724284






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compound 5h had stronger growth inhibitory activity in HepG2, A549, and HT-29 cells than compound 5k, with IC50 values of 2.57, 5.48, and 30.04 muM, respectively. 5h latexin Homo sapiens
2 Compound 5h also inhibited the growth of other cells lines, including Hep3B, PLC/PRF5, SMMC-7721, HeLa, and A375, with IC50 values of 2.76, 4.26, 29.66, 18.86, and 10.21 muM, respectively. 5h latexin Homo sapiens