Title : 2'-Deoxycytidine protects normal human bone marrow progenitor cells in vitro against the cytotoxicity of 3'-azido-3'-deoxythymidine with preservation of antiretroviral activity.

Pub. Date : 1989 Nov 1

PMID : 2572282






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1 We examined, in vitro, the effect of high, but clinically achievable and nontoxic, concentrations of 2"-deoxycytidine (dCyd) (greater than or equal to 100 mumol/L) on high-dose AZT mediated growth inhibition and intracellular biochemical perturbations in normal bone marrow progenitor cells. Deoxycytidine Cyd Drosophila melanogaster