Title : 3',4',7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress.

Pub. Date : 2015 Jun

PMID : 25720812






2 Functional Relationships(s)
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1 In addition, pretreatment with THF attenuated H2O2-induced rapid and significant phosphorylation of c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinases (PI3K)/Akt. Hydrogen Peroxide AKT serine/threonine kinase 1 Homo sapiens
2 THF also inhibited nuclear factor-kappaB (NF-kappaB) translocation to the nucleus induced by H2O2, down-stream of H2O2-induced phosphorylation of MAPKs and PI3K/Akt. Hydrogen Peroxide AKT serine/threonine kinase 1 Homo sapiens