Pub. Date : 2015 May 15
PMID : 25715702
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intracellular ATP is also an uncompetitive GLUT1 inhibitor and shares structural similarities with caffeine, suggesting that caffeine acts at the previously characterized endofacial GLUT1 nucleotide-binding site. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 2 | Intracellular ATP is also an uncompetitive GLUT1 inhibitor and shares structural similarities with caffeine, suggesting that caffeine acts at the previously characterized endofacial GLUT1 nucleotide-binding site. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 3 | Caffeine and ATP displace the fluorescent ATP derivative, trinitrophenyl-ATP, from the GLUT1 nucleotide-binding site, but d-glucose and the transport inhibitor cytochalasin B do not. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 4 | Caffeine and ATP displace the fluorescent ATP derivative, trinitrophenyl-ATP, from the GLUT1 nucleotide-binding site, but d-glucose and the transport inhibitor cytochalasin B do not. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 5 | Like ATP, caffeine renders the GLUT1 carboxy-terminus less accessible to peptide-directed antibodies, but cytochalasin B and d-glucose do not. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 6 | Caffeine binding to GLUT1 mimics the action of ATP but not cytochalasin B on sugar transport. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |