Title : Influence of histamine on the expression of CCL20 in human gingival fibroblasts.

Pub. Date : 2015 Dec

PMID : 25712856






2 Functional Relationships(s)
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1 RESULTS: In HGFs, histamine induced expression of CCL20 and IL8 genes in a time-dependent manner (p < 0.05). Histamine C-X-C motif chemokine ligand 8 Homo sapiens
2 Combined stimulation with histamine and Pam3CSK4 or LPS led to a significant amplification in expression of CCL20 and IL-8 when compared with treatment with each stimulant alone (p < 0.05), and this effect was mediated via pathways involving the H1R (p < 0.05). Histamine C-X-C motif chemokine ligand 8 Homo sapiens