Title : The Effect of Simvastatin on Infection-Induced Inflammatory Response of Human Fetal Membranes.

Pub. Date : 2015 Jul

PMID : 25704622






1 Functional Relationships(s)
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1 Pre-treatment with simvastatin (S-L) reduced IL-6 (P = 0.02), TNF-alpha (P = 0.02), and MMP-9 (P = 0.01); post-treatment (L-S) reduced IL-1beta (P = 0.02) and TNF-alpha (P = 0.04), while simultaneous treatment (L+S) did not reduce any of the cytokines tested. Simvastatin interleukin 6 Homo sapiens