Title : Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.

Pub. Date : 2015 Jul

PMID : 25704105






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Independently, genetic deletion of both MT1 and MT2 receptors in a melatonin-proficient mouse strain (C3H) resulted in significantly more nicotine consumption than controls. Nicotine metallothionein 1 Mus musculus
2 The fact that expression of either the MT1 or MT2 melatonin receptor is sufficient to maintain lower nicotine consumption suggests functional overlap and potential mechanistic explanations. Nicotine metallothionein 1 Mus musculus