Pub. Date : 2015 May
PMID : 25701613
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, 24days of imipramine treatment in RSD mice significantly decreased stress-induced mRNA levels for IL-6 in brain microglia. | Imipramine | interleukin 6 | Mus musculus |
| 2 | Following ex vivo LPS stimulation, microglia from mice exposed to RSD, had higher mRNA expression of IL-6, TNF-alpha, and IL-1beta, and this was reversed by imipramine treatment. | Imipramine | interleukin 6 | Mus musculus |
| 3 | In a second experiment, imipramine was added to drinking water confirming the reversal of social avoidant behavior and decrease in mRNA expression of IL-6 in microglia. | Imipramine | interleukin 6 | Mus musculus |