Pub. Date : 2015 Feb 20
PMID : 25699547
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition to the expected activation of Btk by membranes containing phosphatidylinositol triphosphate (PIP3), we found that inositol hexakisphosphate (IP6), a soluble signaling molecule found in both animal and plant cells, also activates Btk. | Phytic Acid | Bruton tyrosine kinase | Homo sapiens |
| 2 | In addition to the expected activation of Btk by membranes containing phosphatidylinositol triphosphate (PIP3), we found that inositol hexakisphosphate (IP6), a soluble signaling molecule found in both animal and plant cells, also activates Btk. | Phytic Acid | Bruton tyrosine kinase | Homo sapiens |
| 3 | Sequence comparisons with other Tec-family kinases suggest that activation by IP6 is unique to Btk. | Phytic Acid | Bruton tyrosine kinase | Homo sapiens |