Title : Semisynthetic Studies on and Biological Evaluation of N-Methyllaurotetanine Analogues as Ligands for 5-HT Receptors.

Pub. Date : 2015 Apr 24

PMID : 25695425






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The commercially available alkaloid boldine (2) was used as the starting material for synthesis of various C-9 alkoxy analogues of N-methyllaurotetanine in order to gauge the effect of C-9 alkylation on affinity and selectivity at 5-HT1A, 5-HT2A, and 5-HT7 receptors. Alkaloids 5-hydroxytryptamine receptor 2A Homo sapiens