Title : Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.

Pub. Date : 2015 Aug

PMID : 25694334






1 Functional Relationships(s)
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1 This lysine conjugate is currently being considered for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer, and combines the anti-HER2 antibody trastuzumab (Herceptin( )), with the cytotoxic microtubule-inhibiting maytansine derivative, DM1. Lysine immunoglobulin heavy diversity 1-7 Homo sapiens