Title : PI3P binding by Atg21 organises Atg8 lipidation.

Pub. Date : 2015 Apr 1

PMID : 25691244






2 Functional Relationships(s)
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1 Here, we show that Atg21, a WD40 beta-propeller, binds via PI3P to the preautophagosomal structure (PAS). Aminosalicylic Acid WD repeat domain, phosphoinositide interacting 2 Homo sapiens
2 Atg21 thus defines PI3P-dependently the lipidation site by linking and organising the E3 ligase complex and Atg8 at the PAS. Aminosalicylic Acid WD repeat domain, phosphoinositide interacting 2 Homo sapiens