Title : Inhibitory effect of triterpenoids from Dillenia serrata (Dilleniaceae) on prostaglandin E2 production and quantitative HPLC analysis of its koetjapic acid and betulinic acid contents.

Pub. Date : 2015 Feb 16

PMID : 25690285






2 Functional Relationships(s)
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1 Three triterpenoids isolated from the root bark of the plant, koetjapic (1), 3-oxoolean-12-en-30-oic (2), and betulinic (3) acids, exhibited significant concentration-dependent inhibitory effects on PGE2 production with IC50 values of 1.05, 1.54, and 2.59 muM, respectively, as compared with the positive control, indomethacin (IC50 = 0.45 muM). triterpenoids latexin Homo sapiens
2 Three triterpenoids isolated from the root bark of the plant, koetjapic (1), 3-oxoolean-12-en-30-oic (2), and betulinic (3) acids, exhibited significant concentration-dependent inhibitory effects on PGE2 production with IC50 values of 1.05, 1.54, and 2.59 muM, respectively, as compared with the positive control, indomethacin (IC50 = 0.45 muM). triterpenoids latexin Homo sapiens