Title : Celecoxib Combined with Diacerein Effectively Alleviates Osteoarthritis in Rats via Regulating JNK and p38MAPK Signaling Pathways.

Pub. Date : 2015 Aug

PMID : 25687638






1 Functional Relationships(s)
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1 Furthermore, the protein expression of downstream genes of JNK, including activating-transcription factor (Atf-2), matrix metalloproteinase-13 (MMP-13), and cyclooxygenase (COX-2), were also significantly inhibited by CLX combined with DC as compared with single treatments. Celecoxib cytochrome c oxidase II, mitochondrial Rattus norvegicus