Title : Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.

Pub. Date : 2016

PMID : 25687583






1 Functional Relationships(s)
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Protein Name
Organism
1 The R and S form of thiophene based pyrazolines-carboxamides showed a binding energy and inhibition constant between 7.93 to -8.76 and 1.54 to 0.38 muM toward MAO-A and -6.39 to -8.51 and 20.84 to 0.57 muM toward MAO-B respectively. Thiophenes monoamine oxidase A Homo sapiens