Title : The effects of cimetidine, ranitidine and famotidine on rat hepatic microsomal cytochrome P-450 activities.

Pub. Date : 1989 Apr

PMID : 2568738






2 Functional Relationships(s)
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1 We studied the effect of cimetidine, ranitidine and famotidine on the monoxygenase, the oxidase and the peroxidase action of cytochrome P-450. Ranitidine cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
2 Ranitidine and famotidine (both pharmacodynamically more potent than cimetidine) only slightly affected cytochrome P-450 activities. Ranitidine cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus