Title : Effects of receptor tyrosine kinase inhibitors on VEGF165 a- and VEGF165 b-stimulated gene transcription in HEK-293 cells expressing human VEGFR2.

Pub. Date : 2015 Jun

PMID : 25684635






1 Functional Relationships(s)
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1 KEY RESULTS: VEGF(165)a produced a concentration-dependent activation of the NFAT-luciferase reporter gene in living cells that was inhibited in a non-competitive fashion by four different RTKIs (cediranib, pazopanib, sorafenib and vandetanib). vandetanib vascular endothelial growth factor A Homo sapiens