Title : The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.

Pub. Date : 2015 Mar 15

PMID : 25681332






1 Functional Relationships(s)
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1 In a mouse peritonitis model of gout, using monosodium urate crystals to activate NLRP3, 15d-PGJ2 caused a significant inhibition of cell recruitment and associated IL-1beta release. Uric Acid interleukin 1 beta Mus musculus