Title : Localization of Atg3 to autophagy-related membranes and its enhancement by the Atg8-family interacting motif to promote expansion of the membranes.

Pub. Date : 2015 Mar 12

PMID : 25680528






2 Functional Relationships(s)
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1 We also find that mutations in the Atg8-family interacting motif (AIM) of Atg3 significantly impairs the PAS/IM localization of Atg3, resulting in inefficient IM expansion. Aminosalicylic Acid ubiquitin-like protein ATG8 Saccharomyces cerevisiae S288C
2 It is suggested that the AIM-mediated PAS/IM localization of Atg3 facilitates membrane expansion in these structures probably by ensuring active production of Atg8-PE on the membranes. Aminosalicylic Acid ubiquitin-like protein ATG8 Saccharomyces cerevisiae S288C