Pub. Date : 2015 May
PMID : 25678418
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 6beta-Hydroxylation of many steroids, including cortisol, cortisone, progesterone and testosterone, was catalyzed primarily by CYP3A4. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | CYP1A2 and CYP3A4, respectively, are likely the major hepatic enzymes responsible for 2-/4-hydroxylation and 16alpha-hydroxylation of estradiol and estrone, steroids that can contribute to breast cancer risk. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |