Title : Regioselective hydroxylation of steroid hormones by human cytochromes P450.

Pub. Date : 2015 May

PMID : 25678418






1 Functional Relationships(s)
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1 CYP1A2 and CYP3A4, respectively, are likely the major hepatic enzymes responsible for 2-/4-hydroxylation and 16alpha-hydroxylation of estradiol and estrone, steroids that can contribute to breast cancer risk. Estradiol cytochrome P450 family 3 subfamily A member 4 Homo sapiens