Title : Effect of GSTP1 and ABCC4 gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-5-fluorouracil-based chemotherapy in Bangladeshi breast cancer patients.

Pub. Date : 2015 Jul

PMID : 25677905






1 Functional Relationships(s)
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Protein Name
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1 The most important cytotoxic drug namely, cyclophosphamide used in breast cancer along with epirubicin and 5-fluorouracil, is transported by ABCC transporters and detoxified by glutathione S-transferases (GSTs). Cyclophosphamide ATP binding cassette subfamily C member 1 Homo sapiens